Poly(I:C) induces intense expression of c-IAP2 and cooperates with an IAP inhibitor in induction of apoptosis in cancer cells

BACKGROUND: There is increasing evidence that the toll-like receptor 3 (TLR3) is an interesting target for anti-cancer therapy. Unfortunately, most laboratory investigations about the impact of TLR3 stimulation on human malignant cells have been performed with very high concentrations - 5 to 100 μg/...

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Detalhes bibliográficos
Main Authors: Friboulet, Luc, Gourzones, Claire, Tsao, Sai Wah, Morel, Yannis, Paturel, Carine, Témam, Stéphane, Uzan, Catherine, Busson, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928000/
https://ncbi.nlm.nih.gov/pubmed/20576118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-327
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