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MECHANISMS FOR THE SHUTTLING OF PLASMA NON-TRANSFERRIN-BOUND IRON (NTBI) ONTO DEFEROXAMINE BY DEFERIPRONE

In iron overload conditions, plasma contains non-transferrin bound iron species, collectively referred to as plasma NTBI. These include iron-citrate species, some of which are protein bound. Because NTBI is taken into tissues susceptible to iron loading, its removal by chelation is desirable but onl...

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Detalhes bibliográficos
Main Authors: Evans, Patricia, Kayyali, Reem, Hider, Robert C., Eccleston, John, Porter, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927975/
https://ncbi.nlm.nih.gov/pubmed/20627190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2010.05.002
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