Common Familial Colorectal Cancer Linked to Chromosome 7q31: a genome-wide analysis

Present investigations suggest that approximately 30% of colorectal cancer (CRC) cases arise on the basis of inherited factors. We hypothesize that the majority of inherited factors are moderately penetrant genes, common in the population. We use an affected sibling pair approach to identify genetic...

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Autori principali: Neklason, Deborah W., Kerber, Richard A., Nilson, David B., Anton-Culver, Hoda, Schwartz, Ann G., Griffin, Constance A., Lowery, Jan T., Schildkraut, Joellen M., Evans, James P., Tomlinson, Gail E., Strong, Louise C., Miller, Alexander R., Stopfer, Jill E., Finkelstein, Dianne M., Nadkarni, Prakash M., Kasten, Carol H., Mineau, Geraldine P., Burt, Randall W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927856/
https://ncbi.nlm.nih.gov/pubmed/18974144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1376
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