Tumor response to radiotherapy is dependent on genotype-associated mechanisms in vitro and in vivo

BACKGROUND: We have previously shown that in vitro radiosensitivity of human tumor cells segregate non-randomly into a limited number of groups. Each group associates with a specific genotype. However we have also shown that abrogation of a single gene (p21) in a human tumor cell unexpectedly sensit...

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Detalhes bibliográficos
Main Authors: Williams, Jerry R, Zhang, Yonggang, Zhou, Haoming, Gridley, Daila S, Koch, Cameron J, Dicello, John F, Slater, James M, Little, John B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927609/
https://ncbi.nlm.nih.gov/pubmed/20704711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-5-71
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