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CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion

BACKGROUND: Ovarian carcinoma (OvCa) is the most lethal gynecological malignancy among women and its poor prognosis is mainly due to metastasis. Chemokine receptor CCR9 is primarily expressed by a small subset of immune cells and its only natural ligand, CCL25, is largely expressed in the thymus, wh...

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Detalhes bibliográficos
Main Authors: Johnson, Erica L, Singh, Rajesh, Singh, Shailesh, Johnson-Holiday, Crystal M, Grizzle, William E, Partridge, Edward E, Lillard, James W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927595/
https://ncbi.nlm.nih.gov/pubmed/20649989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-8-62
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