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Mechanisms of mono- and poly-ubiquitination: Ubiquitination specificity depends on compatibility between the E2 catalytic core and amino acid residues proximal to the lysine

Ubiquitination involves the attachment of ubiquitin to lysine residues on substrate proteins or itself, which can result in protein monoubiquitination or polyubiquitination. Ubiquitin attachment to different lysine residues can generate diverse substrate-ubiquitin structures, targeting proteins to d...

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Detalhes bibliográficos
Main Authors: Sadowski, Martin, Sarcevic, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927562/
https://ncbi.nlm.nih.gov/pubmed/20704751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-5-19
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