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Predicting the reactivity of proteins from their sequence alone: Kazal family of protein inhibitors of serine proteinases

An additivity-based sequence to reactivity algorithm for the interaction of members of the Kazal family of protein inhibitors with six selected serine proteinases is described. Ten consensus variable contact positions in the inhibitor were identified, and the 19 possible variants at each of these po...

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Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Lu, Stephen M., Lu, Wuyuan, Qasim, M. A., Anderson, Stephen, Apostol, Izydor, Ardelt, Wojciech, Bigler, Theresa, Chiang, Yi Wen, Cook, James, James, Michael N. G., Kato, Ikunoshin, Kelly, Clyde, Kohr, William, Komiyama, Tomoko, Lin, Tiao-Yin, Ogawa, Michio, Otlewski, Jacek, Park, Soon-Jae, Qasim, Sabiha, Ranjbar, Michael, Tashiro, Misao, Warne, Nicholas, Whatley, Harry, Wieczorek, Anna, Wieczorek, Maciej, Wilusz, Tadeusz, Wynn, Richard, Zhang, Wenlei, Laskowski, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2001
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171964/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.031581398
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