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Molecular Targeting of Intracellular Compartments Specifically in Cancer Cells

We have implemented a strategy in which a genetically engineered, single-chain protein specifically recognizes cancer cells and is trafficked to a targeted subcellular compartment, such as the nucleus. The recombinant protein termed IL-13.E13K-D2-NLS has a triple functional property: (1) it binds a...

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Detalhes bibliográficos
Main Authors: Pandya, Hetal, Gibo, Denise M., Debinski, Waldemar
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926990/
https://ncbi.nlm.nih.gov/pubmed/20740056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910375274
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