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Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation

The cellular response to Nutlin-3, a small-molecule inhibitor of the p53 repressor MDM2, varies widely among human cancer-derived cell types. Whereas HCT116 colorectal carcinoma cells display sustained cell cycle arrest, BV173 leukemia cells undergo rapid apoptosis and other cell lines show an inter...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: París, Ramiro, Henry, Ryan E., Stephens, Sarah J., McBryde, Meagan, Espinosa, Joaquín M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926973/
https://ncbi.nlm.nih.gov/pubmed/18677110
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