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Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus

Loss of synaptic integrity in the hippocampus and prefrontal cortex (PFC) may play an integral role in age-related cognitive decline. Previously, we showed age-related increases in the dendritic marker microtubule associated protein 2 (MAP-2) and the synaptic marker synaptophysin (SYN) in mice. Simi...

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Detalhes bibliográficos
Main Authors: Haley, Gwendolen E., Kohama, Steven G., Urbanski, Henryk F., Raber, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926858/
https://ncbi.nlm.nih.gov/pubmed/20640549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-010-9137-9
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