Tumor-Stromal Interactions Influence Radiation Sensitivity in Epithelial- versus Mesenchymal-Like Prostate Cancer Cells

HS-27a human bone stromal cells, in 2D or 3D coultures, induced cellular plasticity in human prostate cancer ARCaP(E) and ARCaP(M) cells in an EMT model. Cocultured ARCaP(E) or ARCaP(M) cells with HS-27a, developed increased colony forming capacity and growth advantage, with ARCaP(E) exhibiting the...

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Detalhes bibliográficos
Main Authors: Josson, Sajni, Sharp, Starlette, Sung, Shian-Ying, Johnstone, Peter A. S., Aneja, Ritu, Wang, Ruoxiang, Gururajan, Murali, Turner, Timothy, Chung, Leland W. K., Yates, Clayton
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926670/
https://ncbi.nlm.nih.gov/pubmed/20798867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/232831
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