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A dumbbell probe-mediated rolling circle amplification strategy for highly sensitive microRNA detection

We herein report the design of a dumbbell-shaped DNA probe that integrates target-binding, amplification and signaling within one multifunctional design. The dumbbell probe can initiate rolling circle amplification (D-RCA) in the presence of specific microRNA (miRNA) targets. This D-RCA-based miRNA...

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Detalhes bibliográficos
Main Authors: Zhou, Yuntao, Huang, Qing, Gao, Jimin, Lu, Jianxin, Shen, Xizhong, Fan, Chunhai
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926626/
https://ncbi.nlm.nih.gov/pubmed/20547593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq556
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