Загрузка...

Knocking down gene function with an RNA aptamer expressed as part of an intron

We developed a powerful expression system to produce aptamers and other types of functional RNA in yeast to examine their effects. Utilizing the intron homing process, the aptamer-coding sequences were integrated into hundreds of rRNA genes, and the aptamers were transcribed at high levels by RNA po...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Wang, Shengchun, Zhao, Xiaoching, Suran, Robert, Vogt, Volker M., Lis, John T., Shi, Hua
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926621/
https://ncbi.nlm.nih.gov/pubmed/20542918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq529
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!