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The MAP Kinase Pmk1 and Protein Kinase A Are Required for Rotenone Resistance in the Fission Yeast, Schizosaccharomyces pombe

Rotenone is a widely used pesticide that induces Parkinson's disease-like symptoms in rats and death of dopaminergic neurons in culture. Although rotenone is a potent inhibitor of complex I of the mitochondrial electron transport chain, it can induce death of dopaminergic neurons independently...

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Detalhes bibliográficos
Main Authors: Wang, Yiwei, Gulis, Galina, Buckner, Scott, Johnson, P. Connor, Sullivan, Daniel, Busenlehner, Laura, Marcus, Stevan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926249/
https://ncbi.nlm.nih.gov/pubmed/20655879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.014
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