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Ultrastructural Characterization of the Optic Pathway in a Mouse Model of Neurofibromatosis-1 Optic Glioma

The purpose of this study was to investigate the progression of changes in retinal ganglion cells and optic nerve glia in neurofibromatosis-1 (NF1) genetically-engineered mice with optic glioma. Optic glioma tumors were generated in Nf1+/− mice lacking Nf1 expression in GFAP+ cells (astrocytes). Sta...

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Hlavní autoři: KIM, K-.Y., JU, W-. K., HEGEDUS, B., GUTMANN, D. H., ELLISMAN, M. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926211/
https://ncbi.nlm.nih.gov/pubmed/20600672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.06.017
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