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Sustained Sleep Fragmentation Results in Delayed Changes in Hippocampal-Dependent Cognitive Function Associated with Reduced Dentate Gyrus Neurogenesis
Sleep fragmentation (SF) is prevalent in human sleep-related disorders. In rats, sustained SF has a potent suppressive effect on adult hippocampal dentate gyrus (DG) neurogenesis. Adult-generated DG neurons progressively mature over several weeks, and participate in certain hippocampal-dependent cog...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2926207/ https://ncbi.nlm.nih.gov/pubmed/20600652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.06.038 |
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