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Biotin Synthesis Begins by Hijacking the Fatty Acid Synthetic Pathway

Although biotin is an essential enzyme cofactor found in all three domains of life, our knowledge of its biosynthesis remains fragmentary. Most of the carbon atoms of biotin are derived from pimelic acid, a seven carbon dicarboxylic acid, but the mechanism whereby Escherichia coli assembles this int...

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Detalhes bibliográficos
Main Authors: Lin, Steven, Hanson, Ryan E., Cronan, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925990/
https://ncbi.nlm.nih.gov/pubmed/20693992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.420
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