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Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity

BACKGROUND: Topical microbicides, used by women to prevent the transmission of HIV and other sexually transmitted infections are urgently required. Dendrimers are highly branched nanoparticles being developed as microbicides. However, the anti-HIV and HSV structure-activity relationship of dendrimer...

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Bibliographic Details
Main Authors: Tyssen, David, Henderson, Scott A., Johnson, Adam, Sterjovski, Jasminka, Moore, Katie, La, Jennifer, Zanin, Mark, Sonza, Secondo, Karellas, Peter, Giannis, Michael P., Krippner, Guy, Wesselingh, Steve, McCarthy, Tom, Gorry, Paul R., Ramsland, Paul A., Cone, Richard, Paull, Jeremy R. A., Lewis, Gareth R., Tachedjian, Gilda
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925893/
https://ncbi.nlm.nih.gov/pubmed/20808791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012309
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