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Acetylcholine Receptor-α Subunit Expression in Myasthenia Gravis: A Role for the Autoantigen in Pathogenesis?

BACKGOUND: Previous studies have shown increased expression of AChR alpha (AChR-α) subunit transcripts in myasthenia gravis (MG) and experimental MG (EAMG) but have not examined the functional properties of this overexpression. METHODS: We examined the mRNA and protein expression of AChR-α, as well...

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Detalhes bibliográficos
Main Authors: Sheng, Jian Rong, Li, Liang Cheng, Prabhakar, Bellur S., Meriggioli, Matthew N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925667/
https://ncbi.nlm.nih.gov/pubmed/19609914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.21371
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