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Evolutionary fates within a microbial population highlight an essential role for protein folding during natural selection

Systems biology can offer a great deal of insight into evolution by quantitatively linking complex properties such as protein structure, folding, and function to the fitness of an organism. Although the link between diseases such as Alzheimer's and misfolding is well appreciated, directly showi...

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Detalhes bibliográficos
Main Authors: Peña, Matthew I, Davlieva, Milya, Bennett, Matthew R, Olson, John S, Shamoo, Yousif
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925523/
https://ncbi.nlm.nih.gov/pubmed/20631681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.43
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