Effects of spironolactone on atrial structural remodelling in a canine model of atrial fibrillation produced by prolonged atrial pacing

BACKGROUND AND PURPOSE: Suppression of the renin-angiotensin-aldosterone system can prevent atrial fibrillation (AF) by attenuating atrial structural remodelling but the role of aldosterone in AF prevention has not been investigated thoroughly. We explored whether the aldosterone antagonist, spirono...

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Detalhes bibliográficos
Main Authors: Zhao, J, Li, J, Li, W, Li, Y, Shan, H, Gong, Y, Yang, B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Paper with Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925482/
https://ncbi.nlm.nih.gov/pubmed/20082611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00551.x
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