Effects of mitochondrial dysfunction on the immunological properties of microglia

BACKGROUND: Neurodegenerative diseases are characterized by both mitochondrial dysfunction and activation of microglia, the macrophages of the brain. Here, we investigate the effects of mitochondrial dysfunction on the activation profile of microglial cells. METHODS: We incubated primary mouse micro...

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Detalhes bibliográficos
Main Authors: Ferger, Annette I, Campanelli, Loretta, Reimer, Valentina, Muth, Katharina N, Merdian, Irma, Ludolph, Albert C, Witting, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925359/
https://ncbi.nlm.nih.gov/pubmed/20701773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-45
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