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Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct
Regulatory T cells, Tregs, are a subset of lymphocytes that have immunosuppressive attributes. They are elevated in blood of glioblastoma patients and within this tumor's tissue itself. Indoleamine 2,3-dioxygenase, IDO, converts tryptophan to kynurenine. IDO activity enhances Treg formation by...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925358/ https://ncbi.nlm.nih.gov/pubmed/20691089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-44 |
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