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Structural features in the Rous sarcoma virus RNA stability element are necessary for sensing the correct termination codon

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is an mRNA quality control mechanism that selectively recognizes and targets for degradation mRNAs containing premature termination codons. Retroviral full-length RNA is presented to the host translation machinery with characteristics rarely observed am...

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Detalhes bibliográficos
Main Authors: Withers, Johanna B, Beemon, Karen L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925335/
https://ncbi.nlm.nih.gov/pubmed/20687936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-65
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