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Crystal structure of the α(6)β(6) holoenzyme of propionyl-coenzyme A carboxylase
Propionyl-coenzyme A carboxylase (PCC), a mitochondrial biotin-dependent enzyme, is essential for the catabolism of the amino acids Thr, Val, Ile and Met, cholesterol, and fatty acids with an odd number of carbon atoms. Deficiencies of PCC activity in humans are linked to the disease propionic acide...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925307/ https://ncbi.nlm.nih.gov/pubmed/20725044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09302 |
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