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t(3;17)(p25;q21) APL Represents a Cryptic Insertion of PML-RARA into the 3p25 Locus

We previously reported a case of a 72 year old man with acute promyelocytic leukemia with karyotype 47XYt(3;17)(p25;q21), +8. Fluorescent in-situ hybridization failed to show rearrangement of the PML locus but did demonstrate relocalization of the retinoic acid receptor alpha (RARA) to chromosome 3....

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Detalhes bibliográficos
Main Authors: Chattopadhyay, Anuja, Redner, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925300/
https://ncbi.nlm.nih.gov/pubmed/20633765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2010.05.001
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