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Aging Impairs the Unfolded Protein Response to Sleep Deprivation and Leads to Proapoptotic Signaling
Protein misfolding, accumulation, and aggregation characterize many aging-related diseases. Protein aggregates do not accumulate in unstressed cells primarily because of the existence of competent cellular “quality control” machinery. The endoplasmic reticulum (ER) is a major part of this quality co...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925257/ https://ncbi.nlm.nih.gov/pubmed/18579727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5685-07.2008 |
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