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A Phase I-II Study of Combined Blockade of the ErbB Receptor Network with Trastuzumab and Gefitinib in Patients with HER2 (ErbB2)-Overexpressing Metastatic Breast Cancer

PURPOSE: To determine the safety, and efficacy of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in combination with trastuzumab in patients with metastatic HER2-positive metastatic breast cancer. EXPERIMENTAL DESIGN: Patients with HER2-overexpressing breast cancer were tre...

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Autors principals: Arteaga, Carlos L., O’Neill, Anne, Moulder, Stacy L., Pins, Michael, Sparano, Joseph A., Sledge, George W., Davidson, Nancy E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925197/
https://ncbi.nlm.nih.gov/pubmed/18829509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0482
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