Protective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particles

We generated influenza virus-like particles (VLPs) containing the wild type (WT) H5 hemagglutinin (HA) from A/Viet Nam/1203/04 virus or a mutant H5 HA with a deletion of the multibasic cleavage motif. VLPs containing mutant H5 HA were found to be as immunogenic as VLPs containing WT HA. A single int...

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Detalhes bibliográficos
Main Authors: Song, Jae-Min, Hossain, Md. Jaber, Yoo, Dae-Goon, Lipatov, Aleksandr S., Davis, C. Todd, Quan, Fu-Shi, Chen, Li-Mei, Hogan, Jeff, Donis, Ruben O., Compans, Richard W., Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925114/
https://ncbi.nlm.nih.gov/pubmed/20580392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.05.034
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