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Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer

Sensory hair cells in the mammalian cochlea convert mechanical stimuli into electrical impulses that subserve audition1,2. Loss of hair cells and their innervating neurons is the most frequent cause of hearing impairment3. Atonal homolog 1 (Atoh1, also known as Math1) is a basic helix-loop-helix tra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gubbels, Samuel. P., Woessner, David W., Mitchell, John C., Ricci, Anthony J., Brigande, John V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925035/
https://ncbi.nlm.nih.gov/pubmed/18754012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07265
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