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Mycophenolic acid may delay allograft fibrosis by inhibiting TGF-β1-induced activation of Nox-2 via the NF-κB pathway
BACKGROUND: We evaluated the role of renal tubular Nox-2 in the pathogenesis of epithelial-to-mesenchymal transition (EMT) in kidney allografts. METHODS: We examined this question in human kidney allografts with tubulointerstitial fibrosis not otherwise specified (IFTANOS), in the Fisher to Lewis ra...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924925/ https://ncbi.nlm.nih.gov/pubmed/20548261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181e6ae0a |
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