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A heterogeneous “resting” pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses

Using pHluorin-tagged synaptic vesicle proteins we have examined the partitioning of these probes into recycling and non-recycling pools at hippocampal nerve terminals in cell culture. Our studies show that for 3 of the major synaptic vesicle components, vGlut-1, VAMP-2 and Synaptotagmin I, ∼50-60%...

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Détails bibliographiques
Auteurs principaux: Fernandez-Alfonso, Tomas, Ryan, Timothy A.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924874/
https://ncbi.nlm.nih.gov/pubmed/18941900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11068-008-9030-y
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