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Neurons don't appreciate FUSsing in the cytoplasm

Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is characterized by degeneration of motor neurons. In this issue of The EMBO Journal, Dormann et al. link ALS-associated mutations in the FUS protein with alterations in nuclear import and stress granule formation.

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Detalhes bibliográficos
Main Authors: Buratti, Emanuele, Baralle, Francisco E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924646/
https://ncbi.nlm.nih.gov/pubmed/20717146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.163
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