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Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans

Several previous genome-wide and targeted association studies revealed that variants in the CHRNA5-CHRNA3-CHRNB4 (CHRNA5/A3/B4) gene cluster on chromosome 15 that encode the α5, α3 and β4 subunits of the nicotinic acetylcholine receptor (nAChRs) are associated with nicotine dependence (ND) in Europe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Ming D., Xu, Qing, Lou, Xiang-Yang, Payne, Thomas J, Niu, Tianhua, Ma, Jennie Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924635/
https://ncbi.nlm.nih.gov/pubmed/19859904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.31043
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