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Delay-induced Degrade-and-Fire Oscillations in Small Genetic Circuits

Robust oscillations have recently been observed in a synthetic gene network composed of coupled positive and negative feedback loops. Here we use deterministic and stochastic modeling to investigate how a small time delay in such regulatory networks can lead to strongly nonlinear oscillations that c...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Mather, William, Bennett, Matthew R., Hasty, Jeff, Tsimring, Lev S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924583/
https://ncbi.nlm.nih.gov/pubmed/19257639
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