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Delay-induced Degrade-and-Fire Oscillations in Small Genetic Circuits
Robust oscillations have recently been observed in a synthetic gene network composed of coupled positive and negative feedback loops. Here we use deterministic and stochastic modeling to investigate how a small time delay in such regulatory networks can lead to strongly nonlinear oscillations that c...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924583/ https://ncbi.nlm.nih.gov/pubmed/19257639 |
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