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Applications of proteomic technologies for understanding the premature proteolysis of CFTR
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, which encodes an ATP-dependent anion channel. Disease-causing mutations can affect channel biogenesis, trafficking or function, and result in reduced ion transport at the apical surface of many tis...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924573/ https://ncbi.nlm.nih.gov/pubmed/20653504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/epr.10.42 |
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