Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients

Vaccination with idiotype (Id) protein-pulsed dendritic cells (DCs) has been explored in multiple myeloma and the results have been disappointing. To improve the efficacy of DC vaccination in myeloma, we investigated the use of Id- and keyhole limpet haemocyanin (KLH)-pulsed, CD40 ligand-matured DCs...

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Detaylı Bibliyografya
Asıl Yazarlar: Yi, Qing, Szmania, Susann, Freeman, John, Qian, Jianfei, Rosen, Nancy A., Viswamitra, Sanjaya, Cottler-Fox, Michele, Barlogie, Bart, Tricot, Guido, van Rhee, Frits
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924470/
https://ncbi.nlm.nih.gov/pubmed/20618329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2010.08286.x
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