Mucosal Delivery of Human Papillomavirus Pseudovirus-Encapsidated Plasmids Improves Potency of DNA Vaccination

Mucosal immunization may be important for protection against pathogens whose transmission and pathogenesis target mucosal tissue. The capsid proteins of human papillomavirus (HPV) confer tropism for basal epithelium and can encapsidate DNA during self-assembly to form pseudovirions (PsV). Therefore,...

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Main Authors: Graham, Barney S., Kines, Rhonda, Corbett, Kizzmekia S., Nicewonger, John, Johnson, Teresa R., Chen, Man, LaVigne, Daaimah, Roberts, Jeffrey N., Cuburu, Nicolas, Schiller, John T., Buck, Christopher B.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924464/
https://ncbi.nlm.nih.gov/pubmed/20555315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.31
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