Paucity of Initial Cerebrospinal Fluid Inflammation in Cryptococcal Meningitis is associated with subsequent Immune Reconstitution Inflammatory Syndrome

BACKGROUND: Cryptococcal meningitis (CM)-related immune reconstitution inflammatory syndrome (IRIS) complicates antiretroviral therapy (ART) in 20–40% of ART-naïve persons with AIDS and prior CM. Pathogenesis is unknown. METHODS: We compared initial CSF cultures, inflammatory markers and cytokine pr...

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Main Authors: Boulware, David R., Bonham, Shulamith C., Meya, David B., Wiesner, Darin L., Park, Gregory S., Kambugu, Andrew, Janoff, Edward N., Bohjanen, Paul R
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924457/
https://ncbi.nlm.nih.gov/pubmed/20677939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/655785
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