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Small Molecule Functional Analogs of Peptides that Inhibit λ Site-specific Recombination and Bind Holliday Junctions

Our lab has isolated hexameric peptides that are structure-selective ligands of Holliday junctions (HJ), central intermediates of several DNA recombination reactions. One of the most potent of these inhibitors, WRWYCR, has shown antibacterial activity in part due to its inhibition of DNA repair prot...

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Autori principali: Ranjit, Dev K., Rideout, Marc C., Nefzi, Adel, Ostresh, John M., Pinilla, Clemencia, Segall, Anca M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924435/
https://ncbi.nlm.nih.gov/pubmed/20598532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.06.029
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