Immune Modulation with Sulfasalazine Attenuates Immunopathogenesis but Enhances Macrophage-Mediated Fungal Clearance during Pneumocystis Pneumonia

Although T cells are critical for host defense against respiratory fungal infections, they also contribute to the immunopathogenesis of Pneumocystis pneumonia (PcP). However, the precise downstream effector mechanisms by which T cells mediate these diverse processes are undefined. In the current stu...

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Autores principales: Wang, Jing, Gigliotti, Francis, Bhagwat, Samir P., George, Thaddeus C., Wright, Terry W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924364/
https://ncbi.nlm.nih.gov/pubmed/20808846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001058
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