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A Global Overview of the Genetic and Functional Diversity in the Helicobacter pylori cag Pathogenicity Island

The Helicobacter pylori cag pathogenicity island (cagPAI) encodes a type IV secretion system. Humans infected with cagPAI–carrying H. pylori are at increased risk for sequelae such as gastric cancer. Housekeeping genes in H. pylori show considerable genetic diversity; but the diversity of virulence...

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Detalhes bibliográficos
Main Authors: Olbermann, Patrick, Josenhans, Christine, Moodley, Yoshan, Uhr, Markus, Stamer, Christiana, Vauterin, Marc, Suerbaum, Sebastian, Achtman, Mark, Linz, Bodo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924317/
https://ncbi.nlm.nih.gov/pubmed/20808891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001069
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