Brg-1 mediates the constitutive and fenretinide-induced expression of SPARC in mammary carcinoma cells via its interaction with transcription factor Sp1

BACKGROUND: Secreted protein, acidic and rich in cysteine (SPARC) is a matricellular protein that mediates cell-matrix interactions. It has been shown, depending on the type of cancer, to possess either pro- or anti-tumorigenic properties. The transcriptional regulation of the SPARC gene expression...

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Hlavní autoři: Xu, Yong Zhong, Heravi, Mitra, Thuraisingam, Thusanth, Marco, Sergio Di, Muanza, Thierry, Radzioch, Danuta
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924311/
https://ncbi.nlm.nih.gov/pubmed/20687958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-210
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