Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription Factor

During the G2 phase of the cell cycle, the Aurora-A kinase plays an important role in centrosome maturation and progression to mitosis. In this study, we show in colorectal cell lines that Aurora-A expression is downregulated in response to topoisomerase I inhibition. Using chromatin immunoprecipita...

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Detalhes bibliográficos
Main Authors: Courapied, Sandy, Cherier, Julia, Vigneron, Arnaud, Troadec, Marie-Bérangère, Giraud, Sandrine, Valo, Isabelle, Prigent, Claude, Gamelin, Erick, Coqueret, Olivier, Barré, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924310/
https://ncbi.nlm.nih.gov/pubmed/20682043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-205
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