Impact of central and peripheral TRPV1 and ROS levels on proinflammatory mediators and nociceptive behavior

BACKGROUND: Transient receptor potential vanilloid 1 (TRPV1) channels are important membrane sensors on peripheral nerve endings and on supportive non-neuronal synoviocytes in the knee joint. TRPV 1 ion channels respond with activation of calcium and sodium fluxes to pH, thermal, chemical, osmotic,...

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Autores principales: Westlund, Karin N, Kochukov, Mikhail Y, Lu, Ying, McNearney, Terry A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924298/
https://ncbi.nlm.nih.gov/pubmed/20691059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-46
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