Continuing or adding IL-2 in patients treated with antiretroviral therapy (ACTG Protocol A5051, a rollover trial of ACTG Protocol A328)

BACKGROUND: Effective antiretroviral therapy reduces HIV-1 RNA levels, improves CD4 T-cell counts, and lowers the risk of opportunistic infections and malignancies. Interleukin-2 (IL-2) has been shown to increase CD4 T-cell numbers mainly by expanding CD4 cells and by prolonging their half-lives. HI...

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Main Authors: Bosch, Ronald J, Pollard, Richard B, Landay, Alan, Aga, Evgenia, Fox, Lawrence, Mitsuyasu, Ronald
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924251/
https://ncbi.nlm.nih.gov/pubmed/20687947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-7-30
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