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Role of the polycytin-primary cilia complex in bone development and mechanosensing
Pkd1 encodes PC1, a transmembrane receptor-like protein, and Pkd2 encodes PC2, a calcium channel, which interact to form functional polycystin complexes that are widely expressed in many tissues and cell types. The study of autosomal dominant polycystic kidney disease (ADPKD), caused by inactivating...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2010
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924156/ https://ncbi.nlm.nih.gov/pubmed/20392267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05239.x |
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