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Role of the polycytin-primary cilia complex in bone development and mechanosensing

Pkd1 encodes PC1, a transmembrane receptor-like protein, and Pkd2 encodes PC2, a calcium channel, which interact to form functional polycystin complexes that are widely expressed in many tissues and cell types. The study of autosomal dominant polycystic kidney disease (ADPKD), caused by inactivating...

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Detalhes bibliográficos
Main Authors: Xiao, Z.S., Quarles, L.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924156/
https://ncbi.nlm.nih.gov/pubmed/20392267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05239.x
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