Effect of divalent cations and pH on intrinsic factor-mediated attachment of vitamin B(12) to intestinal microvillous membranes

Calcium, but not other divalent cations, is required for optimal uptake of intrinsic factor-bound (57)Co-labeled cyanocobalamin (IFB(12)) by microvillous membranes isolated from hamster ileal-absorptive cells. Chelation of divalent cations by disodium ethylenediaminetetraacetate (EDTA) promptly remo...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Mackenzie, Iain L., Donaldson, Robert M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1972
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4629440/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107060
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