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Calcineurin-mediated Dephosphorylation of Synaptotagmin VI Is Necessary for Acrosomal Exocytosis

Regulated secretion is a fundamental process underlying the function of many cell types. In particular, acrosomal exocytosis in mammalian sperm is essential for egg fertilization. In general, exocytosis is initiated by a cytosolic calcium increase. In this report we show that calcium affects several...

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Библиографические подробности
Главные авторы: Castillo Bennett, Jimena, Roggero, Carlos M., Mancifesta, Franco E., Mayorga, Luis S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924044/
https://ncbi.nlm.nih.gov/pubmed/20551332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095752
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